diff --git a/README.md b/README.md
index 9d9a6a41e..a09749a49 100644
--- a/README.md
+++ b/README.md
@@ -260,10 +260,30 @@ For models compatible with Ascend Extension for PyTorch (torch_npu). To get star
 3. Next, install the necessary packages for torch-npu by adhering to the platform-specific instructions on the [Installation](https://ascend.github.io/docs/sources/pytorch/install.html#pytorch) page.
 4. Finally, adhere to the [ComfyUI manual installation](#manual-install-windows-linux) guide for Linux. Once all components are installed, you can run ComfyUI as described earlier.
 
+### UV (Package Manager)
+
+UV is an extremely fast Python package and project manager, written in Rust. For UV installation, checks [docs](https://docs.astral.sh/uv/). UV help isolation and reproducibility of the desired environment.
+
+```bash
+git clone https://github.com/comfyanonymous/ComfyUI.git # Clone this repo
+cd ComfyUI                                              # Move to created folder
+uv add -r requirements.txt                  # Add dependencies
+```
 
 # Running
 
-```python main.py```
+```bash
+python main.py
+```
+
+If using **UV**:
+
+```bash
+uv run main.py
+# or in case of activating the virtual env before
+source .venv/bin/activate
+python main.py
+```
 
 ### For AMD cards not officially supported by ROCm