diff --git a/tests/v1/core/test_kv_cache_utils.py b/tests/v1/core/test_kv_cache_utils.py
index 24611a4aaa1b..12ed59b6e863 100644
--- a/tests/v1/core/test_kv_cache_utils.py
+++ b/tests/v1/core/test_kv_cache_utils.py
@@ -1436,6 +1436,65 @@ def test_get_kv_cache_config_one_worker():
         ],
     )
 
+    # 6 full + 5 sliding, pad to 6 full + 6 sliding. This is a typical case for gpt-oss
+    # eagle where there is only one more full attention layer than sliding window layers
+    kv_cache_specs_hybrid = {
+        "layer_1": new_kv_cache_spec(),
+        "layer_2": new_kv_cache_spec(),
+        "layer_3": new_kv_cache_spec(),
+        "layer_4": new_kv_cache_spec(),
+        "layer_5": new_kv_cache_spec(),
+        "layer_6": new_kv_cache_spec(),
+        "layer_7": new_sliding_window_spec(),
+        "layer_8": new_sliding_window_spec(),
+        "layer_9": new_sliding_window_spec(),
+        "layer_10": new_sliding_window_spec(),
+        "layer_11": new_sliding_window_spec(),
+    }
+
+    kv_cache_config_hybrid = get_kv_cache_configs(
+        vllm_config, [kv_cache_specs_hybrid], [mem_per_block_per_layer * 6 * 32]
+    )[0]
+    print(kv_cache_config_hybrid)
+    assert kv_cache_config_hybrid == KVCacheConfig(
+        num_blocks=32,
+        kv_cache_tensors=[
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_1", "layer_7"],
+            ),
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_2", "layer_8"],
+            ),
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_3", "layer_9"],
+            ),
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_4", "layer_10"],
+            ),
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_5", "layer_11"],
+            ),
+            KVCacheTensor(
+                size=mem_per_block_per_layer * 32,
+                shared_by=["layer_6"],
+            ),
+        ],
+        kv_cache_groups=[
+            KVCacheGroupSpec(
+                ["layer_1", "layer_2", "layer_3", "layer_4", "layer_5", "layer_6"],
+                new_kv_cache_spec(),
+            ),
+            KVCacheGroupSpec(
+                ["layer_7", "layer_8", "layer_9", "layer_10", "layer_11"],
+                new_sliding_window_spec(),
+            ),
+        ],
+    )
     # different hidden size
     kv_cache_specs_hybrid = {
         "layer_1": new_kv_cache_spec(head_size=128),
diff --git a/vllm/v1/core/kv_cache_utils.py b/vllm/v1/core/kv_cache_utils.py
index b18ba8e8b2c7..a0033fa650ba 100644
--- a/vllm/v1/core/kv_cache_utils.py
+++ b/vllm/v1/core/kv_cache_utils.py
@@ -971,7 +971,16 @@ def _get_kv_cache_groups_uniform_page_size(
     # is the minimum number of layers among all attention types. Need a better
     # strategy if we want to support more complex patterns (e.g., 20 full + 30
     # sw, where the group size should be 10).
-    group_size = min([len(layers) for layers in same_type_layers.values()])
+    min_num_layers = min([len(layers) for layers in same_type_layers.values()])
+    group_size = min_num_layers
+    max_num_layers = max([len(layers) for layers in same_type_layers.values()])
+    if max_num_layers < min_num_layers * 1.25:
+        # If the number of layers is not much larger than the minimum number of layers,
+        # use the maximum number of layers as the group size to avoid too many padding
+        # layers. A typical example is gpt-oss-20b + eagle, with 12 sw + 13 full. We
+        # pad it to (13 sw, 13 full) instead of (12 sw, 24 full). 1.25 is just a
+        # magic number to avoid too many padding layers.
+        group_size = max_num_layers
     grouped_layers = []
     for layers in same_type_layers.values():
         num_padding_layers = group_size - len(layers) % group_size