diff --git a/tests/models/language/generation/test_hybrid.py b/tests/models/language/generation/test_hybrid.py
index eba14e64553e..e4294512338b 100644
--- a/tests/models/language/generation/test_hybrid.py
+++ b/tests/models/language/generation/test_hybrid.py
@@ -104,7 +104,6 @@ def test_models(
                 m.setenv("VLLM_ATTENTION_BACKEND", "FLASHINFER")
             with vllm_runner(model,
                              max_num_seqs=MAX_NUM_SEQS,
-                             enforce_eager=True,
                              enable_prefix_caching=False) as vllm_model:
                 vllm_v1_outputs = vllm_model.generate_greedy_logprobs(
                     example_prompts, max_tokens, num_logprobs)
diff --git a/vllm/config.py b/vllm/config.py
index 384cb584fa9a..a9720fa3142c 100644
--- a/vllm/config.py
+++ b/vllm/config.py
@@ -4312,6 +4312,7 @@ class CompilationConfig:
             self.splitting_ops = [] if self.full_cuda_graph else [
                 "vllm.unified_attention",
                 "vllm.unified_attention_with_output",
+                "vllm.mamba_mixer2",
             ]
 
 
diff --git a/vllm/model_executor/layers/mamba/mamba_mixer2.py b/vllm/model_executor/layers/mamba/mamba_mixer2.py
index f3850d31c829..e32b2be4d40e 100644
--- a/vllm/model_executor/layers/mamba/mamba_mixer2.py
+++ b/vllm/model_executor/layers/mamba/mamba_mixer2.py
@@ -13,7 +13,7 @@ from vllm.distributed import (divide, get_tensor_model_parallel_rank,
                               get_tensor_model_parallel_world_size,
                               tensor_model_parallel_all_gather,
                               tensor_model_parallel_all_reduce)
-from vllm.forward_context import get_forward_context
+from vllm.forward_context import ForwardContext, get_forward_context
 from vllm.model_executor.custom_op import CustomOp
 from vllm.model_executor.layers.linear import (ColumnParallelLinear,
                                                RowParallelLinear)
@@ -33,6 +33,8 @@ from vllm.model_executor.model_loader.weight_utils import (
     LoaderFunction, composed_weight_loader, sharded_weight_loader)
 from vllm.model_executor.models.mamba_cache import MambaCacheParams
 from vllm.model_executor.utils import set_weight_attrs
+from vllm.platforms import current_platform
+from vllm.utils import direct_register_custom_op
 from vllm.v1.attention.backends.mamba_attn import Mamba2AttentionMetadata
 
 # Added by the IBM Team, 2024
@@ -424,14 +426,36 @@ class MambaMixer2(MambaBase, CustomOp):
     def forward_native(
         self,
         hidden_states: torch.Tensor,
-        conv_state: torch.Tensor,
-        ssm_state: torch.Tensor,
+        output: torch.Tensor,
+        mamba_cache_params: MambaCacheParams,
+        mamba2_metadata: Mamba2Metadata,
+        mup_vector: Optional[torch.Tensor] = None,
     ):
         pass
 
+    def forward(
+        self,
+        hidden_states: torch.Tensor,
+        output: torch.Tensor,
+        mamba_cache_params: MambaCacheParams,
+        mamba2_metadata: Mamba2Metadata,
+        mup_vector: Optional[torch.Tensor] = None,
+    ):
+        if not envs.VLLM_USE_V1:
+            CustomOp.forward(self, hidden_states, output, mamba_cache_params,
+                             mamba2_metadata, mup_vector)
+        else:
+            torch.ops.vllm.mamba_mixer2(
+                hidden_states,
+                output,
+                self.prefix,
+                mup_vector,
+            )
+
     def forward_cuda(
         self,
         hidden_states: torch.Tensor,
+        output: torch.Tensor,
         mamba_cache_params: MambaCacheParams,
         mamba2_metadata: Mamba2Metadata,
         mup_vector: Optional[torch.Tensor] = None,
@@ -517,6 +541,7 @@ class MambaMixer2(MambaBase, CustomOp):
         num_prefill_tokens = attn_metadata.num_prefill_tokens  # token count
         has_prefill = num_prefills > 0
         has_decode = num_decodes > 0
+        num_actual_tokens = num_prefill_tokens + num_decodes
 
         # NOTE: V0 put prefill before decode, v1 puts decode before prefill
         # Separate prefill and decode by splitting varlen input
@@ -524,18 +549,18 @@ class MambaMixer2(MambaBase, CustomOp):
         # NOTE: V0 put prefill before decode, v1 puts decode before prefill
         if envs.VLLM_USE_V1:
             hidden_states_B_C_d, hidden_states_B_C_p = torch.split(
-                hidden_states_B_C,
+                hidden_states_B_C[:num_actual_tokens],
                 [num_decodes, num_prefill_tokens],
                 dim=0,
             )
             dt_d, dt_p = torch.split(
-                dt,
+                dt[:num_actual_tokens],
                 [num_decodes, num_prefill_tokens],
                 dim=0,
             )
             # Split along batch dimension
             state_indices_tensor_d, state_indices_tensor_p = torch.split(
-                state_indices_tensor,
+                state_indices_tensor[:num_actual_tokens],
                 [num_decodes, num_prefills],
                 dim=0,
             )
@@ -696,11 +721,10 @@ class MambaMixer2(MambaBase, CustomOp):
         # GatedRMSNorm internally applying SiLU to the gate
         # SiLU is applied internally before normalization, unlike standard
         # norm usage
-        hidden_states = self.norm(hidden_states, gate)
+        hidden_states = self.norm(hidden_states, gate[:num_actual_tokens])
 
         # 5. Final linear projection
-        out, _ = self.out_proj(hidden_states)
-        return out
+        output[:num_actual_tokens], _ = self.out_proj(hidden_states)
 
     def get_state_shape(self) -> tuple[tuple[int, ...], tuple[int, ...]]:
         return get_mamba_state_shape(
@@ -712,3 +736,36 @@ class MambaMixer2(MambaBase, CustomOp):
             state_size=self.ssm_state_size,
             conv_kernel=self.conv_kernel_size,
         )
+
+
+def mamba_mixer2(
+    hidden_states: torch.Tensor,
+    output: torch.Tensor,
+    layer_name: str,
+    mup_vector: Optional[torch.Tensor] = None,
+) -> None:
+    forward_context: ForwardContext = get_forward_context()
+    self = forward_context.no_compile_layers[layer_name]
+    self.forward_cuda(hidden_states=hidden_states,
+                      output=output,
+                      mamba_cache_params=None,
+                      mamba2_metadata=None,
+                      mup_vector=mup_vector)
+
+
+def mamba_mixer2_fake(
+    hidden_states: torch.Tensor,
+    output: torch.Tensor,
+    layer_name: str,
+    mup_vector: Optional[torch.Tensor] = None,
+) -> None:
+    return
+
+
+direct_register_custom_op(
+    op_name="mamba_mixer2",
+    op_func=mamba_mixer2,
+    mutates_args=["output"],
+    fake_impl=mamba_mixer2_fake,
+    dispatch_key=current_platform.dispatch_key,
+)
diff --git a/vllm/model_executor/models/bamba.py b/vllm/model_executor/models/bamba.py
index e93d4294a62c..0f5494427634 100644
--- a/vllm/model_executor/models/bamba.py
+++ b/vllm/model_executor/models/bamba.py
@@ -11,6 +11,7 @@ from transformers import BambaConfig
 
 from vllm import envs
 from vllm.attention.layer import Attention
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import CacheConfig, VllmConfig
 from vllm.distributed import get_tensor_model_parallel_world_size
 from vllm.distributed.parallel_state import get_pp_group
@@ -122,11 +123,10 @@ class BambaMixerDecoderLayer(nn.Module):
             hidden_states, residual = self.input_layernorm(
                 hidden_states, residual)
 
-        hidden_states = self.mamba(hidden_states, mamba_cache_params,
-                                   mamba2_metadata)
+        output = torch.empty_like(hidden_states)
+        self.mamba(hidden_states, output, mamba_cache_params, mamba2_metadata)
         # Fully Connected
-        hidden_states, residual = self.pre_ff_layernorm(
-            hidden_states, residual)
+        hidden_states, residual = self.pre_ff_layernorm(output, residual)
         hidden_states = self.feed_forward(hidden_states)
         return hidden_states, residual
 
@@ -169,7 +169,7 @@ class BambaAttentionDecoderLayer(nn.Module):
         self.max_position_embeddings = max_position_embeddings
 
         if hasattr(config, "partial_rotary_factor"):
-            rotary_dim = self.head_dim * config.partial_rotary_factor
+            rotary_dim = int(self.head_dim * config.partial_rotary_factor)
         elif hasattr(config, "attn_rotary_emb"):
             rotary_dim = config.attn_rotary_emb  # for backward compatibility
         else:
@@ -258,6 +258,7 @@ ALL_DECODER_LAYER_TYPES = {
 }
 
 
+@support_torch_compile
 class BambaModel(nn.Module):
 
     def __init__(self, *, vllm_config: VllmConfig, prefix: str = ""):
diff --git a/vllm/model_executor/models/falcon_h1.py b/vllm/model_executor/models/falcon_h1.py
index 7761de224c9d..6a58b1501fe6 100644
--- a/vllm/model_executor/models/falcon_h1.py
+++ b/vllm/model_executor/models/falcon_h1.py
@@ -10,6 +10,7 @@ from transformers import FalconH1Config
 
 from vllm import envs
 from vllm.attention.layer import Attention
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import CacheConfig, VllmConfig
 from vllm.distributed import get_tensor_model_parallel_world_size
 from vllm.distributed.parallel_state import get_pp_group
@@ -179,13 +180,15 @@ class FalconH1SSMDecoderLayer(nn.Module):
         mamba2_metadata: Mamba2Metadata,
         **kwargs,
     ):
-        hidden_states = self.mamba(
+        output = torch.empty_like(hidden_states)
+        self.mamba(
             hidden_states,
+            output,
             mamba_cache_params,
             mamba2_metadata=mamba2_metadata,
             mup_vector=self.mup_vector,
         )
-        return hidden_states, residual
+        return output, residual
 
 
 class FalconH1AttentionDecoderLayer(nn.Module):
@@ -398,6 +401,7 @@ class FalconH1ParallelHybrid(nn.Module):
         return hidden_states
 
 
+@support_torch_compile
 class FalconH1Model(nn.Module):
 
     def __init__(self, *, vllm_config: VllmConfig, prefix: str = ""):
diff --git a/vllm/model_executor/models/granitemoehybrid.py b/vllm/model_executor/models/granitemoehybrid.py
index 1c93e90737ad..59c1dce48ee7 100644
--- a/vllm/model_executor/models/granitemoehybrid.py
+++ b/vllm/model_executor/models/granitemoehybrid.py
@@ -11,6 +11,7 @@ from transformers import GraniteMoeHybridConfig
 
 from vllm import envs
 from vllm.attention.layer import Attention
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import CacheConfig, VllmConfig
 from vllm.distributed import get_tensor_model_parallel_world_size
 from vllm.distributed.parallel_state import get_pp_group
@@ -104,9 +105,9 @@ class GraniteMoeHybridMambaDecoderLayer(nn.Module):
     ):
         residual = hidden_states
         hidden_states = self.input_layernorm(hidden_states)
-        hidden_states = self.mamba(hidden_states, mamba_cache_params,
-                                   mamba2_metadata)
-        hidden_states = residual + hidden_states * self.residual_multiplier
+        output = torch.empty_like(hidden_states)
+        self.mamba(hidden_states, output, mamba_cache_params, mamba2_metadata)
+        hidden_states = residual + output * self.residual_multiplier
 
         residual = hidden_states
         hidden_states = self.post_attention_layernorm(hidden_states)
@@ -307,6 +308,7 @@ ALL_DECODER_LAYER_TYPES = {
 }
 
 
+@support_torch_compile
 class GraniteMoeHybridModel(nn.Module):
 
     def __init__(self, *, vllm_config: VllmConfig, prefix: str = ""):
diff --git a/vllm/model_executor/models/mamba2.py b/vllm/model_executor/models/mamba2.py
index d812d8cc0a39..adad181617e6 100644
--- a/vllm/model_executor/models/mamba2.py
+++ b/vllm/model_executor/models/mamba2.py
@@ -10,6 +10,7 @@ from transformers import MambaConfig
 
 from vllm import envs
 from vllm.attention.backends.abstract import AttentionMetadata
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import VllmConfig
 from vllm.distributed.parallel_state import get_pp_group
 from vllm.forward_context import get_forward_context
@@ -79,11 +80,12 @@ class Mamba2DecoderLayer(nn.Module):
         else:
             hidden_states, residual = self.norm(hidden_states, residual)
 
-        hidden_states = self.mixer(hidden_states, mamba_cache_params,
-                                   mamba2_metadata)
-        return hidden_states, residual
+        output = torch.empty_like(hidden_states)
+        self.mixer(hidden_states, output, mamba_cache_params, mamba2_metadata)
+        return output, residual
 
 
+@support_torch_compile
 class Mamba2Model(nn.Module):
 
     def __init__(self, *, vllm_config: VllmConfig, prefix: str = ""):
diff --git a/vllm/model_executor/models/nemotron_h.py b/vllm/model_executor/models/nemotron_h.py
index cf7b39db1fe3..6a999e2254e7 100644
--- a/vllm/model_executor/models/nemotron_h.py
+++ b/vllm/model_executor/models/nemotron_h.py
@@ -25,6 +25,7 @@ from torch import nn
 
 from vllm import envs
 from vllm.attention.layer import Attention
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import CacheConfig, VllmConfig
 from vllm.distributed import get_tensor_model_parallel_world_size
 from vllm.distributed.parallel_state import get_pp_group
@@ -172,9 +173,9 @@ class NemotronHMambaDecoderLayer(nn.Module):
         else:
             hidden_states, residual = self.norm(hidden_states, residual)
 
-        hidden_states = self.mixer(hidden_states, mamba_cache_params,
-                                   mamba2_metadata)
-        return hidden_states, residual
+        output = torch.empty_like(hidden_states)
+        self.mixer(hidden_states, output, mamba_cache_params, mamba2_metadata)
+        return output, residual
 
 
 class NemotronHAttention(nn.Module):
@@ -292,6 +293,7 @@ ALL_DECODER_LAYER_TYPES = {
 }
 
 
+@support_torch_compile
 class NemotronHModel(nn.Module):
 
     def __init__(self, *, vllm_config: VllmConfig, prefix: str = ""):
diff --git a/vllm/model_executor/models/zamba2.py b/vllm/model_executor/models/zamba2.py
index ebf8dd497f67..7764fd9b9e08 100644
--- a/vllm/model_executor/models/zamba2.py
+++ b/vllm/model_executor/models/zamba2.py
@@ -17,6 +17,7 @@ from transformers import Zamba2Config
 
 from vllm import envs
 from vllm.attention.layer import Attention
+from vllm.compilation.decorators import support_torch_compile
 from vllm.config import CacheConfig, VllmConfig
 from vllm.distributed import get_tensor_model_parallel_world_size
 from vllm.forward_context import get_forward_context
@@ -548,14 +549,16 @@ class Zamba2MambaDecoderLayer(nn.Module):
         hidden_states = self.input_layernorm(hidden_states)
 
         # Process through Mamba mixer
-        hidden_states = self.mamba(
+        output = torch.empty_like(hidden_states)
+        self.mamba(
             hidden_states,
+            output,
             mamba_cache_params=mamba_cache_params,
             mamba2_metadata=mamba2_metadata,
         )
 
         # residual connection after mamba
-        hidden_states = residual + hidden_states
+        hidden_states = residual + output
 
         return hidden_states
 
@@ -646,6 +649,7 @@ class Zamba2HybridLayer(nn.Module):
         return layer_outputs
 
 
+@support_torch_compile
 class Zamba2Model(nn.Module):
     """Core Zamba2 model combining transformer and Mamba architectures.
     
diff --git a/vllm/v1/worker/gpu_model_runner.py b/vllm/v1/worker/gpu_model_runner.py
index d5449a68bc28..1ee9c070226c 100644
--- a/vllm/v1/worker/gpu_model_runner.py
+++ b/vllm/v1/worker/gpu_model_runner.py
@@ -2753,9 +2753,6 @@ class GPUModelRunner(LoRAModelRunnerMixin):
             if self.vllm_config.speculative_config is not None:
                 raise NotImplementedError(
                     "Mamba with speculative decoding is not supported yet.")
-            if not self.vllm_config.model_config.enforce_eager:
-                raise NotImplementedError(
-                    "Mamba with cuda graph is not supported yet.")
             if self.vllm_config.cache_config.enable_prefix_caching:
                 raise NotImplementedError(
                     "Prefix caching is not supported for Mamba yet.")