diff --git a/vllm/v1/worker/tpu_worker.py b/vllm/v1/worker/tpu_worker.py
index 9a380373d461..4d9a113e39ee 100644
--- a/vllm/v1/worker/tpu_worker.py
+++ b/vllm/v1/worker/tpu_worker.py
@@ -113,9 +113,16 @@ class TPUWorker:
         # can have slightly different XLA graphs.
         world_size = self.parallel_config.world_size
         rank = xr.global_ordinal()
-        per_rank_path = os.path.join(envs.VLLM_XLA_CACHE_PATH,
-                                     f"tp{world_size}_rank{rank}")
-        xr.initialize_cache(per_rank_path, readonly=False)
+        # The PyTorch/XLA compilation cache uses the Torch IR to generate keys.
+        # Consequently, changes in optimization flags, which affect compilation
+        # results, don't change the cache key. This can result in the wrong
+        # compilation being used. To prevent this, disabling the XLA compilation
+        # cache during development is recommended.We can disable it by
+        # `export VLLM_XLA_CACHE_PATH=`
+        if envs.VLLM_XLA_CACHE_PATH:
+            per_rank_path = os.path.join(envs.VLLM_XLA_CACHE_PATH,
+                                         f"tp{world_size}_rank{rank}")
+            xr.initialize_cache(per_rank_path, readonly=False)
 
         # Init ModelRunner here, so that we have access to self.device.
         self.model_runner = TPUModelRunner(self.vllm_config, self.device)
diff --git a/vllm/worker/tpu_worker.py b/vllm/worker/tpu_worker.py
index 66911790662e..71b4b38fb9d6 100644
--- a/vllm/worker/tpu_worker.py
+++ b/vllm/worker/tpu_worker.py
@@ -93,9 +93,16 @@ class TPUWorker(LoRANotSupportedWorkerBase, LocalOrDistributedWorkerBase):
         # can have slightly different XLA graphs.
         world_size = self.parallel_config.world_size
         rank = xr.global_ordinal()
-        per_rank_path = os.path.join(envs.VLLM_XLA_CACHE_PATH,
-                                     f"tp{world_size}_rank{rank}")
-        xr.initialize_cache(per_rank_path, readonly=False)
+        # The PyTorch/XLA compilation cache uses the Torch IR to generate keys.
+        # Consequently, changes in optimization flags, which affect compilation
+        # results, don't change the cache key. This can result in the wrong
+        # compilation being used. To prevent this, disabling the XLA compilation
+        # cache during development is recommended.We can disable it by
+        # `export VLLM_XLA_CACHE_PATH=`
+        if envs.VLLM_XLA_CACHE_PATH:
+            per_rank_path = os.path.join(envs.VLLM_XLA_CACHE_PATH,
+                                         f"tp{world_size}_rank{rank}")
+            xr.initialize_cache(per_rank_path, readonly=False)
 
         self.profiler = None
         if envs.VLLM_TORCH_PROFILER_DIR and self.rank < 1: